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Abstract #0887

Motion correction in post-injection dynamic cardiac T 1 -mapping: preliminary results

Anne Menini 1,2 , Pauline Ferry 3 , Marine Beaumont 4,5 , Jeffrey A. Stainsby 6 , Glenn S. Slavin 7 , Laurent Bonnemains 5 , Jacques Felblinger 1,4 , and Freddy Odille 3

1 IADI, Universit de Lorraine, Nancy, France, 2 Global Research, GE, Garching b. Mnchen, Germany, 3 U947, INSERM, Nancy, France, 4 CIC, INSERM, Nancy, France, 5 CHU Nancy, Nancy, France, 6 Healthcare, GE, Toronto, ON, Canada, 7 Healthcare, GE, Bethesda, MD, United States

Dynamic quantification of myocardial T 1 pre- and post-injection is a useful tool to evaluate fibrosis. These quantifications require numerous acquisitions and are therefore very sensible to inter- and intra-acquisition motion, especially in patients who can barely hold their breath. Here, we propose a motion compensation method that can be applied on multi-contrast acquisitions by taking advantage of redundant information. This motion correction was applied on data sets acquired in free-breathing in two patients with Duchenne Muscular Dystrophy. The proposed method was shown to improve the differentiation between regions of the myocardium with different stages of fibrosis.

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