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Abstract #0892

Monitoring multiple sclerosis lesions over a period of five years using MR frequency shift imaging

Vanessa Wiggermann 1,2 , Enedino Hernndez Torres 1,3 , Irene M. Vavasour 1,3 , Alex L. MacKay 2,3 , David K.B. Li 1,3 , Anthony Traboulsee 3,4 , and Alexander Rauscher 1,3

1 Radiology, University of British Columbia, Vancouver, BC, Canada, 2 Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 3 UBC MRI Research Centre, Vancouver, BC, Canada, 4 Neurology, University of British Columbia, Vancouver, BC, Canada

Long-term changes in multiple sclerosis (MS) patients are often monitored measuring lesion load and observing changes in size and shape of MS lesions. However, high-spatial resolution tools for the estimation of quantitative changes in MS lesions are still missing. Here, we exploit MR frequency shift imaging as a high-resolution tool to monitor long-term changes in MS lesions. Frequency mapping showed great sensitivity to changes at lesion appearance and at long-term follow up of the same lesions, 3-5 years after appearance.

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