Abstract #0892
Monitoring multiple sclerosis lesions over a period of five years using MR frequency shift imaging
Vanessa Wiggermann 1,2 , Enedino Hernndez Torres 1,3 , Irene M. Vavasour 1,3 , Alex L. MacKay 2,3 , David K.B. Li 1,3 , Anthony Traboulsee 3,4 , and Alexander Rauscher 1,3
1
Radiology, University of British Columbia,
Vancouver, BC, Canada,
2
Physics
and Astronomy, University of British Columbia,
Vancouver, BC, Canada,
3
UBC MRI Research
Centre, Vancouver, BC, Canada,
4
Neurology,
University of British Columbia, Vancouver, BC, Canada
Long-term changes in multiple sclerosis (MS) patients
are often monitored measuring lesion load and observing
changes in size and shape of MS lesions. However,
high-spatial resolution tools for the estimation of
quantitative changes in MS lesions are still missing.
Here, we exploit MR frequency shift imaging as a
high-resolution tool to monitor long-term changes in MS
lesions. Frequency mapping showed great sensitivity to
changes at lesion appearance and at long-term follow up
of the same lesions, 3-5 years after appearance.
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