ACCELERATED ECHO PLANAR J-RESOLVED SPECTROSCOPIC IMAGING IN PROSTATE CANCER: NONLINEAR RECONSTRUCTION USING TOTAL VARIATION AND MAXIMUM ENTROPY
Rajakumar Nagarajan 1 , Zohaib Iqbal 1 , Brian Burns 1 , Neil Wilson 1 , Manoj K Sarma 1 , Daniel A Margolis 1 , Robert E Reiter 2 , Steven S Raman 1 , and M.Albert Thomas 1
Radiological Sciences, University of
California Los Angeles, LOS ANGELES, CA, United States,
University of California Los Angeles, LOS ANGELES, CA,
Prostate cancer is a difficult disease to correctly
diagnose and patients often undergo a painful and
uncomfortable biopsy. The non-uniformly undersampled (NUS)
four-dimensional (4D) echo-planar J-resolved
spectroscopic imaging (EP-JRESI) study aims to establish
data fidelity after non-linear reconstruction and to
detect more metabolites than the currently used
one-dimensional (1D) spectral based MR spectroscopic
imaging method. The maximum entropy (MaxEnt) and total
variation (TV) methods were used for the reconstruction
of the NUS 4D EP-JRESI data. There was an excellent
correlation between the two methods (TV and MaxEnt).
These methods may help clinicians with an improved
diagnosis and on deciding on the best course of
treatment for the patient.
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