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Abstract #0977

Higher anisotropy in Diffusion Spectrum Imaging at longer diffusion times

Steven Baete 1,2 and Fernando Emilio Boada 1,2

1 Center for Biomedical Imaging, Dept. of Radiology, NYU Langone Medical Center, New York, New York, United States, 2 CAI2R, Center for Advanced Imaging Innovation and Research, NYU Langone Medical Center, New York, New York, United States

Diffusion Spectrum Imaging (DSI) would benefit from longer diffusion times as these lead to increased anisotropy due to the restricted/hindered diffusion orthogonal to the fiber bundles. Since longer diffusion times are prohibitive in conventional spin echo sequences due to the concomitant increase in SNR, we investigated the use of a stimulated echo sequence which counters the SNR loss. When comparing DSI datasets acquired with spin echo and stimulated echo diffusion sequences in vivo in a healthy volunteer on a clinical 3T scanner, an increase in anisotropy is noticeable at longer diffusion times. This higher anisotropy might improve fiber tracking results.

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