HS8 saturation pulse train for first-pass myocardial perfusion imaging at 7T
Yuehui Tao 1 , Aaron T. Hess 1 , Graeme A. Keith 1 , Christopher T. Rodgers 1 , Alexander Liu 1 , Jane M. Francis 1 , Stefan Neubauer 1 , and Matthew D. Robson 1
University of Oxford Centre for Clinical
Magnetic Resonance Research, University of Oxford,
Oxford, United Kingdom
First-pass myocardial perfusion imaging is used
clinically but would benefit from improvements, which
might be expected at 7T due to higher SNR and longer T1.
But major implementation challenges at 7T are found
owing to the large B0&B1 variations across the heart,
low peak B1, and SAR restrictions that make uniform
saturation extremely difficult to achieve. We propose a
train of four HS8 pulses for saturation in first-pass
myocardial perfusion imaging at 7T, and compare it with
previously proposed solutions in simulation and in-vivo
experiments. We also present the first series of human
first-pass myocardial perfusion images at 7T.
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