Mapping the Distinct Single-Vessel Vascular Contribution to BOLD and CBV fMRI

Hemodynamic signal from individual venules can be detected directly with fMRI. Here, the hemodynamic signal from BOLD and CBV fMRI was measured at high temporal (100ms) and spatial (150x150m) resolution in layers 4/5 of the rat forepaw S1 with a fast gradient-echo MRI sequence. Distinctly different voxels were activated in BOLD vs CBV fMRI. In contrast to the BOLD activated voxels primarily located within penetrating venules, CBV activated voxels were primarily located to penetrating arterioles. This result makes it possible to directly image the CBV and BOLD response at the level of single-vessels to better understand neurovascular coupling.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.