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Abstract #1010

Non Invasive Quantification of Ectopic Fat Content: flexibility with bariatric surgery induced weight loss

Ins ABDESSELAM 1,2 , Bndicte GABORIT 2,3 , Frank KOBER 1 , Alexis JACQUIER 4 , Olivier EMUNGANIA 5 , Marie-Christine ALESSI 2 , Monique BERNARD 1 , and Anne DUTOUR 2,3

1 Facult de mdecine, Aix-Marseille University, CRMBM, CNRS7339, Marseille, France, 2 Facult de mdecine, Aix-Marseille University, NORT, Inserm1062/Inra1260, Marseille, France, 3 Endocrinology, Metabolic diseases and nutrition, CHU Nord, Marseille, France, 4 Radiology, CHU TImone, Marseille, France, 5 Gastroenterology, CHU Nord, Marseille, France

Bariatric surgery (BS) reduce, after 6 months, epicardial fat deposition but doesn't induce any change in myocardial triglyceride content. The aim of this study was to investigate the impact of BS on pancreatic fat content, to determine whether we can reduce myocardial triglyceride content two years after BS and whether decreased level of triglyceride content 6 months after BS could be maintained 2 years later. For that purpose, we used 1H-MRS. Our study provides compelling evidences that pancreatic fat increase with type 2 diabetes and could be decreased with BS. Finally, we show that this decrease is maintained overtime.

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