Differentiation of Brown Adipose Tissue using Manganese Enhanced MRI
Hussein Srour 1 , Anna Ulyanova 1 , and kai Hsiang chuang 1
Singapore Bioimaging Consortium, Singapore,
Manganese-enhanced MRI (MEMRI) is a useful method for
measuring calcium-dependent cellular activity due to
accumulation of Mn2+ in cells via voltage-gated calcium
channels. We investigated the feasibility of MEMRI as a
method to detect BAT activation in mice induced by cold
exposure. We show for the first time that MEMRI can
differentiate between BAT and WAT tissue in mice.
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