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Abstract #1041

Comparison of steady-state and spin-echo DWI based on morphological assessment of breast lesions

Kristin L Granlund 1,2 , Debra Ikeda 1 , Jafi Lipson 1 , Jennifer Kao 1 , Jung Min Chang 3 , Brian Hargreaves 1 , and Bruce Daniel 1

1 Radiology, Stanford University, Stanford, CA, United States, 2 Electrical Engineering, Stanford University, Stanford, CA, United States, 3 Radiology, Seoul National University Hospital, Seoulq, Korea

The DESS sequence has been used to acquire diffusion-weighted images, and this study evaluates DESS images relative to EPI DWI images. Four radiologists were surveyed about the image quality and BI-RADS scores of images containing pathology-proven breast lesions. The DESS sequence acquired sharper diffusion-weighted breast images than EPI (p<0.001). ROC curves were calculated from the BI-RADS scores, and the DESS sequence had a larger AUC (0.74 for DESS, 0.68 for EPI) and a tighter confidence interval. Better image quality facilitates morphological assessment of lesion malignancy.

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