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Abstract #1042

Comparison of the value of DWI based on monoexponential and stretched exponential model in differential diagnosis between benign and malignant lesions of breast

Jie He 1 , Yan Zhang 1 , Jingliang Cheng 1 , Ying Hu 1 , Anfei Wang 1 , Dandan Zheng 2 , and Xiaoyan Wang 1

1 Department of MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, HeNan, China, 2 GE healthcare, Beijing, China

MRI has been widely used in the diagnosis of breast disease. However, the calculation of apparent diffusion coefficient by simple monoexponential relationship between MRI signal and b value does not fully account for tissue behavior. Intravoxel incoherent motion (IVIM) method allows quantitative parameters that reflect tissue micro capillary perfusion and tissue diffusivity. In this study, the stretched-exponential model was used to generate and distributed diffusion coefficient (DDC) maps. The values and DDCs were compared with traditional monoexponential ADC in the differential diagnosis of breast benign and malignant lesions.

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