Abstract #1071
The Effect of Varying Diffusion-Encoding Gradient Strength and Separation on Measured Apparent Diffusion Coefficient and T2 of Prostate
Shiyang Wang 1 , Yahui Peng 1,2 , Milica Medved 1 , Steffen Sammet 1 , Ambereen Yousuf 1 , Weiwei Du 1,3 , Yulei Jiang 1 , Gregory S. Karczmar 1 , and Aytekin Oto 1
1
Department of Radiology, University of
Chicago, Chicago, IL, United States,
2
School
of Electronic and Information Engineering, Beijing
Jiaotong University, Bejing, China,
3
Department
of Information Science, Kyoto Institute of Technology,
Kyoto, Japan
Hybrid DWI and T2 measurements showed improved contrast
enhancement in prostate cancer diagnosis. The measured
apparent diffusion coefficient can be affected by
restricted diffusion, depending on the diffusion
gradient separation (Δ). The effect of diffusion
gradient strength (g) and Δ on prostate cancer diagnosis
is unknown. Current study was performed in order to test
whether acquisitions with longer Δ are affected by
restricted diffusion. ADC/T2s obtained with hybrid DWI
sequences with fixed and non-fixed Δs were compared and
no significant differences were found. Thus restricted
diffusion does not affect the ADC values at the Δ values
used in hybrid imaging.
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