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Abstract #1090

Initial experience: combination of MR pharmacokinetic modeling and FDG uptake using simultaneous dynamic contrast enhanced MRI and PET imaging

Nathaniel E. Margolis 1 , Linda Moy 1 , Akshat C. Pujara 1 , Alana Amarosa 1 , Eric E. Sigmund 1 , Christian Geppert 2 , Christopher Glielmi 2 , Melanie Freed 1 , Li Feng 1 , Ricardo Otazo 1 , Amy N. Melsaether 1 , and Sungheon Kim 1

1 Radiology, NYU Langone Medical Center, New York, New York, United States, 2 Siemens Medical Solutions, New York, New York, United States

The objective of our study was to assess the feasibility of using DCE-MRI and PET data for the assessment of breast cancer MR pharmacokinetics and metabolic activity. A whole-body integrated 3 T PET/MR scanner was used to simultaneously acquire DCE-MRI and PET images of the breast in the prone position. We found trends between DCE-MRI kinetic model parameters, metastatic burden, and progesterone receptor status. Our preliminary results demonstrate the feasibility of using simultaneous acquired DCE-MRI and PET measures for better characterization of breast lesions.

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