Abstract #1099
In Vivo Assessment of Non-Small Cell Lung Cancer: Detection of Early Response to Concurrent Chemoradiotherapy by Using Breath-Hold Dynamic Contrast Enhanced MRI
Xiuli Tao 1 , Han Ouyang 1 , Feng Ye 1 , Zihua Su 2 , Xiao Xu 2 , and Ning Wu 1
1
Cancer HospitalChinese Academy of Medical
Sciences & Peking Union Medical College, Beijing, China,
2
GE
Healthcare, Beijing, China
DCE-MRI has been extensively used in monitoring
treatment response on many anatomies. However, this
technique was not fully explored in lung cancer due to
breathing motion. In this paper, we demonstrated by
using a mutual information based nonlinear registration
scheme and two compartment Tofts model, clinical
relevant parameters could be extracted from a
breath-hold DCE-MRI to monitor treatment response on
NSCLC.
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