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Abstract #1152

Direct imaging of tumor cellularity using restriction spectrum imaging in a xenograft mouse GBM model

Tuva Hope 1,2 , Joshua Kuperman 3 , Anders Dale 3 , and Nate White 3

1 Medical Imaging Lab, NTNU, Trondheim, Trondheim, Norway, 2 Intervention Center, Oslo University Hospital, Oslo, Oslo, Norway, 3 Multimodal Imaging Lab - UCSD, San Diego, United States

Using a GBM xenograft mouse model we demonstrate how restricted water signal, as measured with constant b-value, multi diffusion time diffusion experiment, provides a novel contrast mechanism for identifying cancer cells in vivo.

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