Abstract #1176
Co-registration of Synchrotron Radiation-microCT and micro-MRI images: a new method for the complete characterization of newly-formed bone
Allegra Conti 1 , Raffaele Sinibaldi 1 , Silvia Capuani 2 , Tonino Traini 3 , Gian Luca Romani 1,4 , and Stefania Della Penna 1,4
1
Department of Neuroscience and Imaging,
University of Chieti, Chieti, CH, Italy,
2
Department
of Physics, Sapienza University of Rome, Rome, RM,
Italy,
3
Department
of Stomatology and Biotechnologies, University of
Chieti, Chieti, CH, Italy,
4
Institute
of Advanced Biomedical Technologies, University of
Chieti, Chieti, CH, Italy
The use of biomaterials scaffolds for bone
regeneration/augmentation represents one of the most
used strategies in dentistry to support prosthetic
restorations. Often implant failure can be associated to
the trabecular bone quality of the jaw. Here we present
a new method based on the co-registration of images of
scaffold collected with the X-ray Synchtron Radiation-microCT
and micro-MRI, that permit to obtain a complete and 3D
characterization of scaffolds, distinguishing
unambiguously different degrees of bone mineralization,
multinucleate cells and blood vessels inside the bone
marrow. Until now this was possible only with an
histological, and so bidimensional, evaluation of the
samples.
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