Abstract #1244
In vivo magnetic resonance elastography of the human intervertebral disk: Preliminary results
Kaspar Josche Streitberger 1,2 , Jing Guo 1 , Gerd Diederichs 1 , Sebastian Hirsch 1 , Andreas Fehlner 1 , Jrgen Braun 3 , and Ingolf Sack 1
1
Department of Radiology, Charit -
Universittsmedizin Berlin, Berlin, Berlin, Germany,
2
Department
of Neurology, Charit - Universittsmedizin Berlin,
Berlin, Berlin, Germany,
3
Medical Informatics,
Charit - Universittsmedizin Berlin, Berlin, Berlin,
Germany
The noninvasive detection and quantification of the
human intervertebral disk by MR elastography (MRE) could
be beneficial for the diagnosis of chronic disk
degeneration. This study presents the first in vivo
measurement of viscoelastic constants of the human
intervertebral disc by MRE. Multifrequency MRE and
multifrequency wave field inversion was applied to 15
healthy volunteers one of whom was measured 7 times on 7
different days. The magnitude of the complex shear
modulus measured in the nucleus pulposus (mean value
4.34 1.2 kPa) shows a good reproducibility and
correlates with the MRI morphology based Pfirrmann
score.
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