Abstract #1345
Endoluminal MRI coils for mice rectal wall assessment
Hugo Dorez 1 , Raphal Sablong 1 , Laurence Canaple 2 , Sophie Gaillard 1 , Driffa Moussata 3 , and Olivier Beuf 1
1
Universit de Lyon, CREATIS CNRS UMR 5220
INSERM U1044 INSA Lyon 1, Villeurbanne, Rhne-Alpes,
France,
2
Institut
de Gnomique Fonctionnelle de Lyon, Universit de Lyon
1, UMR 5242 CNRS, Ecole Normale Suprieure de Lyon,
Lyon, Rhne-Alpes, France,
3
Service
hpato-gastroentrologie, Hospice Civil Lyon Sud,
Pierre-Bnite, Rhne-Alpes, France
The purpose of this project research is to assess mice
rectum wall using MRI combined with endomicroscopy and
conventional endoscopy. Endoluminal MRI coils with
active decoupling circuit were developed and
characterized on phantoms. Then, in-vivo examination was
finally done on mice (c57 black6j). Endoluminal coils
improve significantly the local SNR compared to body
mice volume birdcage coil. Rectal wall layers are better
visualized due to improved spatial resolution achieve
with SNR gain. This study shows the feasibility to use
small endoluminal coils for mice rectal wall assessment
and opens perspectives to better understand rectal
pathologies.
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