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Abstract #1346

Double-Resonant 13 C/ 1 H Coil System for { 1 H} 13 C in vivo NMR Spectroscopy on a 7-T Whole-Body MR Tomograph

Tanja Platt 1 , Andreas Korzowski 1 , Reiner Umathum 1 , and Peter Bachert 1

1 Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Baden-Wrttemberg, Germany

13 C NMR spectroscopy enables a noninvasive quantification of various metabolites in vivo (without or with an enrichment of 13 C) and takes advantage of high B 0 and of 1 H-decoupling. The aim of this study was to design, implement and test a surface coil system for in vivo 1 H-decoupled 13 C NMR spectroscopy on an experimental 7-T whole-body MR tomograph. The use of a transmission line resonator concept with special frequency selective filter circuits ensures sufficient electromagnetic decoupling for both frequencies ( 13 C, 1 H). The resulting coil system allows among other applications the acquisition of high resolution 1 H-decoupled 13 C NMR spectra in vivo.

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