Double-Resonant 13 C/ 1 H Coil System for { 1 H} 13 C in vivo NMR Spectroscopy on a 7-T Whole-Body MR Tomograph

¹³ C NMR spectroscopy enables a noninvasive quantification of various metabolites in vivo (without or with an enrichment of ¹³ C) and takes advantage of high B ₀ and of ¹ H-decoupling. The aim of this study was to design, implement and test a surface coil system for in vivo ¹ H-decoupled ¹³ C NMR spectroscopy on an experimental 7-T whole-body MR tomograph. The use of a transmission line resonator concept with special frequency selective filter circuits ensures sufficient electromagnetic decoupling for both frequencies ( ¹³ C, ¹ H). The resulting coil system allows among other applications the acquisition of high resolution ¹ H-decoupled ¹³ C NMR spectra in vivo.

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