Meeting Banner
Abstract #1424

Localized Spectroscopy Without J-modulation at Ultra High Field

Clark Lemke 1 , Uzay Emir 1 , Peter Jezzard 1 , Stuart Clare 1 , and Jamie Near 2

1 FMRIB, University of Oxford, Oxford, Oxfordshire, United Kingdom, 2 Douglas Institute, McGill University, Verdun, Quebec, Canada

In vivo quantification of coupled metabolites is hampered by J-modulation. J-modulation manifests as an echo time (TE) dependent modulation on the metabolite signal leading to increased signal loss over and beyond other relaxation processes. Short TE spectroscopy avoids the effects of J-modulation but is complicated by a broad baseline extending over the relevant frequency range. This baseline can lead to decreased accuracy of metabolite quantification. Here we present a localized metabolite quantification pulse sequence designed to remove J-modulation at long TE (<40 ms) to avoid baseline contamination. The sequence (PRESS-JR) is presented with phantom measurements.

This abstract and the presentation materials are available to members only; a login is required.

Join Here