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Abstract #1425

Functional ASL at 9.4 T a comparison between balanced SSFP and GRE-EPI readout

Jonas Bause 1,2 , Philipp Ehses 1,3 , G. Shajan 1 , Klaus Scheffler 1,3 , and Rolf Pohmann 1

1 High-Field Magnetic Resonance, MPI for biological Cybernetics, Tuebingen, BW, Germany, 2 Graduate Training Center of Neuroscience, International Max-Planck Research School, Tuebingen, BW, Germany, 3 Department for Biomedical Magnetic Resonance, University of Tuebingen, Tuebingen, BW, Germany

Functional ASL has a higher specificity and reproducibility than BOLD fMRI. However, the perfusion related signal is typically in the range of a few percent and the spatial and temporal resolution of arterial spin labeling imaging rather limited. ASL at ultra-high field can benefit from higher intrinsic SNR and increased longitudinal relaxation times. We investigated bSSFP and GRE-EPI as possible readout schemes for fASL studies at 9.4 T and were able to measure the first time stimulus evoked perfusion changes in the human motor cortex at this field strength.

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