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Abstract #1462

Characterizing the Inherent and Noise-Induced Errors in Actual Flip Angle Imaging

M Louis Lauzon 1,2 and Richard Frayne 1,2

1 Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada, 2 Seaman Family MR Research Centre, Calgary, AB, Canada

The flip angle term in an image can be determined using the TR-interleaved AFI (actual flip angle imaging) sequence. AFI makes an approximation, which leads to an inherent bias (a measure of accuracy). Noise propagation, however, produces an uncertainty bias and an increase in the variance (a measure of precision). Here, we analytically and numerically determine the accuracy/precision of the inherent and noise-induced errors of the cosine of the flip angle as a function of various acquisition parameters, and provide an overall error.

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