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Abstract #1487

Accurate And Reliable PC-MRI Sequence To Investigate Complex Dynamic Of Cerebro-Spinal Fluid in the Brain.

Malek I Makki 1 , Christoph Ruegger 2 , Cyrille Capel 3 , Catherine Gondry-Jouet 4 , and Olivier Baledent 5

1 MRI Research Center, University Children Hospital of Zurich, Zurich, Switzerland, 2 Neonatalogy, University Hospital of Zurich, Zurich, Switzerland, 3 Neurosurgery, University Hospital, Amiens, France, 4 Radiology, University Hospital, Amiens, France, 5 Image Processing, University Hospital, Amiens, France

An accurate CSF flow measurement through the pontine cistern is difficult to achieve because of blood flow artifacts from the basilar artery and surrounding vessels. We developed a dedicated PCMRI sequence with pre-saturation double sided bands to suppress signal from blood with no compromise neither on SNR nor on spatio-temporal resolution and validated this on 18 patients with hydrocephalus. We compared the results of the developed sequence in the pontine cistern and foramen of Magendi which is free of blood flow artifact and demonstrated its accuracy and reliability to measuring the stroke volume and the minimum and maximum flow.

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