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Abstract #1488

Multi-contrast inversion-recovery EPI (MI-EPI) functional MRI at 7 T

Ville Renvall 1,2 , Thomas Witzel 1,2 , Marta Bianciardi 1,2 , and Jonathan R. Polimeni 1,2

1 Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2 Department of Radiology, Harvard Medical School, Boston, MA, United States

Multi-contrast inversion-recovery EPI (MI-EPI) was implemented on a 7T system and was used to study brain activations simultaneously using T 1 -, BOLD-, and multiple inversion-recovery-time-signal changes following visual stimulation at a 3-s sampling period. The different contrast images yielded similar activation maps, with extent of activation roughly proportional to the signal levels, but less activation with CSF suppressed rather than gray matter suppressed contrasts. T 1 values were found to significantly increase during visual stimulation concordant with blood volume increases and/or inflow effects.

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