Abstract #1489
7D velocity phase imaging with zoomed simultaneous multi-slice EPI reveals respiration driven motion in brain and CSF
Liyong Chen 1,2 , Alexander Beckett 1,2 , Ajay Verma 3 , and David Feinberg 1,2
1
Helen Wills Neuroscience Institute,
University of California, Berkeley, California, United
States,
2
Advanced
MRI Technologies, LLC, Sebastopol, California, United
States,
3
Biogen Idec, MA, United States
A new highly efficient velocity imaging technique is
developed with simultaneous multi-slice EPI and zoomed
spatial resolution which enables real-time measurement
of CSF and brain velocity. Application of this 7D
imaging technique to normal subjects revealed
respiratory synchronous motion modulating cardiac
waveforms in brain parenchyma and CSF. The brain
pulsations may play a role in clearance of interstitial
fluid in the brain.
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