Abstract #1522
Comparison of semi-LASER localized Brain MRS at 3T and 7T using 32-channel head coils
Subechhya Pradhan 1 , Susanne Bonekamp 1 , Joseph Gillen 1 , Laura Rowland 2 , S. Andrea Wijtenburg 2 , Richard A.E. Edden 1 , and Peter B Barker 1
1
Russell H. Morgan Department of Radiology
and Radiological Science, Johns Hopkins University
School of Medicine, Baltimore, Maryland, United States,
2
Psychiatry,
University of Maryland School of Medicine, Baltimore,
Maryland, United States
MRS is expected to benefit from moving to high field
strengths such as 7T. However, there are also technical
challenges associated with high fields, such as
increased B0 and B1 field inhomogeneities. Therefore, it
is important to compare 7T measurements to those at
lower field. In this study, SNR, linewidths and
Cramer-Rao lower bounds are compared between 3T and 7T
MRS in 3 brain regions of 4 healthy subjects.
Measurements made with near identical methodology at
both field strengths, including 32-channel head coils
and semi-LASER localization. Improvements at 7T were
found in all metrics examined, and were consistent with
expectations.
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