Abstract #1670
On the confounding effect of temperature on chemical shift-encoded fat quantification
Diego Hernando 1 , Samir D. Sharma 1 , Harald Kramer 1,2 , and Scott B. Reeder 1,3
1
Radiology, University of Wisconsin-Madison,
Madison, WI, United States,
2
Ludwig-Maximilians-University
Hospital Munich, Munich, Germany,
3
Medicine,
University of Wisconsin-Madison, Madison, WI, United
States
The proton resonance frequency (PRF) of water depends on
temperature, whereas the PRF of triglycerides is
temperature independent (aside from bulk susceptibility
effects). This leads to a temperature dependence of the
frequency shift between fat and water resonances, which
may introduce errors in chemical shift-encoded (CSE) fat
quantification methods that assume a known relative
shift between the PRF of water and fat. In this work, we
characterize the confounding effect of temperature on
CSE fat quantification. Further, we demonstrate that a
temperature-corrected spectral model of fat can be used
to avoid these errors.
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