Abstract #1727
Multisite DTI of the spinal cord with integrated template and white matter atlas processing pipeline
Julien Cohen-Adad 1,2 , Rebecca S Samson 3 , Torben Schneider 3 , Alex K Smith 4 , Marc Benhamou 1 , Geoffrey Leveque 1 , Seth A Smith 5 , and Claudia A M Wheeler-Kingshott 3
1
Institute of Biomedical Engineering,
Polytechnique Montreal, Montreal, QC, Canada,
2
Functional
Neuroimaging Unit, IUGM, Universite de Montreal,
Montreal, QC, Canada,
3
NMR Research Unit,
Queen Square MS Centre, Department of Neuroinflammation,
UCL Institute of Neurology, United Kingdom,
4
Vanderbilt
University Institute of Imaging Science (VUIIS),
Department of Radiology and Radiological Sciences,
Vanderbilt University, Tennessee, United States,
5
Department
of Biomedical Engineering, Vanderbilt University,
Tennessee, United States
We propose a framework for conducting DTI studies of the
spinal cord across sites equipped with different MRI
systems. The main features are: well-validated
acquisition protocol including reduced field of view
technique, registration to an existing spinal cord
template using state-of-the-art methods and the use of a
white matter atlas for quantifying DTI metrics in
specific spinal tracts. The method is applicable to
other acquisition techniques, such as magnetization
transfer and functional MRI.
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