Abstract #1744
Predicting Myelin Content from Functional Connectivity in the Developing Brain
Jonathan O'Muircheartaigh 1,2 , Douglas C Dean III 2 , Lindsay Walker 2 , Holly Dirks 2 , Nicole Waskiewicz 2 , Irene Piryatinsky 2 , Orla Doyle 1 , and Sean Deoni 2
1
Department of Neuroimaging, King's College
London, London, United Kingdom,
2
Department
of Engineering, Brown University, Providence, Rhode
Island, United States
Resting state fMRI is increasingly being used in
developmental neuroimaging as it can be used during
natural sleep in young infants and toddlers. However,
the developmental trajectory of fMRI connectivity in
this young age range is unclear as is its relationship
with structural connectivity. Here we interrogate the
typical trajectory of functional connectivity and it's
relationship with a quantitative marker of myelin, the
myelin water fraction, in a large cohort of 80 infants
and young children aged 3 to 54 months. We indicate a
linear relationship between myelination and functional
connectivity.
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