Abstract #1756
Functional connectivity differences in full-term and preterm at term equivalent age newborns.
Lara Lordier 1 , Frederic Grouiller 2 , Dimitri Van De Ville 3 , Franois Lazeyras 2 , and Petra S. Hppi 1
1
Division of development and Growth,
Department of pediatrics, Geneva university hospital,
Geneva, Geneva, Switzerland,
2
Departement
of radiology and medical informatics, University of
Geneva, Geneva, Switzerland,
3
Institute
of bioengineering, Ecole Polytechnique Federale de
Lausanne, Lausanne, Switzerland
There is a growing evidence corroborating the hypothesis
that resting-state functional connectivity is related to
both underlying structural connectivity and modulated by
the development of white matter pathways occurring early
in brain development that are maturing throughout
childhood. In this study we compared resting state
functional connectivity using a global group level ICA
in 19 full term newborns and 13 preterm at term
equivalent age infants to assess to which extent
premature exposure to extra-uterine environment impacts
on functional connectivity. The results show significant
differences in functional connectivity between a sensory
area (auditory network) and parts of the salience
networks.
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