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Abstract #1756

Functional connectivity differences in full-term and preterm at term equivalent age newborns.

Lara Lordier 1 , Frederic Grouiller 2 , Dimitri Van De Ville 3 , Franois Lazeyras 2 , and Petra S. Hppi 1

1 Division of development and Growth, Department of pediatrics, Geneva university hospital, Geneva, Geneva, Switzerland, 2 Departement of radiology and medical informatics, University of Geneva, Geneva, Switzerland, 3 Institute of bioengineering, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland

There is a growing evidence corroborating the hypothesis that resting-state functional connectivity is related to both underlying structural connectivity and modulated by the development of white matter pathways occurring early in brain development that are maturing throughout childhood. In this study we compared resting state functional connectivity using a global group level ICA in 19 full term newborns and 13 preterm at term equivalent age infants to assess to which extent premature exposure to extra-uterine environment impacts on functional connectivity. The results show significant differences in functional connectivity between a sensory area (auditory network) and parts of the salience networks.

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