Abstract #1770
Gradient Echo Plural Contrast Imaging in Studying Neonatal Brain Development: Preliminary Results
Jie Wen 1 , Jeffrey J. Neil 1,2 , Joseph Ackerman Jr. 1,2 , Jie Luo 3 , Terri E. Inder 2 , and Dmitriy A. Yablonskiy 1
1
Mallinckrodt Institute of Radiology,
Washington University in St. Louis, St. Louis, MO,
United States,
2
Department
of Pediatrics Newborn Medicine, Washington University in
St. Louis, St. Louis, MO, United States,
3
Massachusetts
Institute of Technology, MA, United States
Different methods have been used in the past to study
brain development. Gradient Echo Plural Contrast Imaging
(GEPCI) is a technique allowing generation of naturally
co-registered images with various contrasts within a
single MRI scan. The quantitative T2* and frequency maps
derived from GEPCI show stronger contrast and more
details compared with conventional clinical images.
Here, we demonstrate the feasibility of applying GEPCI
to evaluation of neonatal brain in health and disease.
Multi-contrast GEPCI images provide multi-perspective
means to explore neonatal brain development and injury
quantitatively. The quantitative R2* distribution
analysis shows substantial differences between term and
preterm borne neonates.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
