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Abstract #1805

Quantification Myelin Mapping Through Short T 1 Component Filtering Linear Combination Using Multi Flip Angle SPGR Data

Zhe Wu 1 , Minming Zhang 2 , Yong Zhang 3 , and Yiping Du 1

1 Department of Biomedical Engineering, Zhejiang University, Hangzhou, Zhejiang, China, 2 Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China, 3 MR Research, GE Healthcare, Shanghai, China

This preliminary study demonstrates the feasibility of myelin water fraction (MWF) mapping through short T 1 component filtering. The data are collected with multi flip angle SPGR sequence and post-processed by linear combination. This new approach provides a fast acquisition and post-processing alternative for quantitative myelin mapping.

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