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Abstract #1834

Cerebrospinal fluid (CSF) outflow tracked with gadolinium-enhanced MRI in cynomolgus monkeys

Kyoung-Min Lee 1 , Jun-Young Chung 2 , Sang-Rae Lee 3 , and Kyu-Tae Chang 3

1 Neurology, Seoul National University Hospital, Seoul, Seoul, Korea, 2 Biomedical Engineering, Gachon University, Incheon, Korea, 3 National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Korea

The pathways and kinetics of cerebrospinal fluid system is imaged using a series of MRI with gadolinium contrast injected via the cistern near foramen magnum of cynomolgus monkeys. The serial images revealed rapid spreading of the contrast agent around the CSF space, followed by slow inflitration to lymphatic system of the neck.

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