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Abstract #1835

Improvements to Time-SLIP Imaging of CSF Flow

Matthew Borzage 1,2 , John Grimm 3 , Tom Perkins 4 , Jon Chia 4 , Gordon McComb 5 , and Stefan Blml 3,6

1 Children's Hospital Los Angeles, Los Angeles, CA, United States, 2 Rudi Schulte Research Institute, Santa Barbara, CA, United States, 3 Radiology, Children's Hospital Los Angeles, CA, United States, 4 Philips Healthcare, OH, United States, 5 Children's Hospital Los Angeles, CA, United States, 6 Rudi Schulte Research Institute, CA, United States

The timeSLIP modality has potential to assist the management of hydrocephalus and related disorders. However, in practice, the variable delay times between tagging and readout result in different levels of background suppression and renders the clinical interpretation sometimes difficult. We tested a new approach, where background signal is constant and flow is visualized with the MR readout occurring at different cardiac cycle time points. Preliminary studies of 17 patients including cases with no CSF flow, or restored CSF flow resulted in imaging results as expected, and a positive change of patient management.

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