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Abstract #1877

Glutamate and GABA Imaging at 7 Tesla

Zhuozhi Dai 1,2 , Tao Zhang 1 , Yanglong Jia 1 , Gen Yan 1 , Gang Xiao 3 , Guishan Zhang 1 , Zhiwei Shen 4 , and Renhua Wu 1

1 Medical Imaging, Shantou University Medical College, Shantou, Guangdong, China, 2 Department of Biomedical Engineering, University of Alberta, Edmonton, AB, Canada, 3 Math and Information Technology, Hanshan Normal University, Guangdong, China, 4 provincial key laboratory of medical molecular imaging, Guangdong, China

Glutamate and GABA are a pair of important neurotransmitters that play a key role in neuropsychiatric diseases. In these studies, we aim to imaging the Glutamte and GABA specifically using chemical exchange saturation transfer technique at 7 Tesla. In addition, we optimized the pre-saturation power respectively and further demonstrated the application in ischemic stroke model in vivo.

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