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Abstract #1913

Studies in Epilepsy Patients using Simultaneous PET/MR: Preliminary Results

Yu-Shin Ding 1,2 , Bangbin Chen 3 , Christopher Glielmi 4 , Timothy Shepherd 1 , Thomas Koesters 1 , Anne-Kristin Vahle 1 , Kent Friedman 1 , Fernando Boada 1 , and Orrin Devinsky 5

1 Radiology, New York University School of Medicine, New York, NY, United States, 2 Psychiatry, New York University School of Medicine, New York, NY, United States, 3 Medical Imaging, National Taiwan University Hospital, Taiwan, 4 Siemens Healthcare, NY, United States, 5 Neurology, New York University School of Medicine, NY, United States

We have initiated a comparative study in neurotypical controls (NC) and epilepsy patients (Epi) using a state-of-the-art PET/MR combined imaging technology with simultaneous acquisition to study epilepsy. With quantitative data analysis on glucose metabolism in over 120 brain regions, we have identified the ROIs showed group differences. The fact that our preliminary results (e.g., abnormal regional glucose metabolism and prevalence of asymmetry) are consistent with the clinical data of epilepsy patients suggests that simultaneous PET/MR imaging provides a useful imaging tool to identify regional abnormality and assist in localizing the seizure focus.

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