Abstract #1925
Altered coupling in triple networks under Parkinson's disease
Lele Xu 1 , Xia Wu 1,2 , and Li Yao 1,2
1
School of Information Science and
Technology, Beijing Normal University, Beijing, Beijing,
China,
2
State
Key Laboratory of Cognitive Neuroscience and Learning,
Beijing Normal University, Beijing, Beijing, China
In this study, the group ICA and correlation analysis
methods were performed to explore and compare the
network coupling in the triple networks, including the
salience network (SN), executive control network (ECN)
and default mode network (DMN), for Parkinsons disease
(PD) patients and normal controls. The results revealed
decreased coupling between SN and ECN for PD patients,
suggesting that SN may less focus on the processing of
external stimuli for PD patients. Furthermore, the
results also showed the decreased coupling between SN
and DMN, indicating that for PD patients, SN may also
less mediate the processing of internal events.
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