Diffusion Tensor Imaging Reveals White Matter Damage in the Optic Nerves of Alzheimers Patients

Optic nerves of Alzheimers Disease (AD) patients were analyzed with diffusion tensor imaging (DTI) and compared to control patients. DTI scans were obtained from the Alzheimers Disease Neuroimaging Initiative (ADNI) database. Signs of white matter damage, including decreased fractional anisotropy, increased radial diffusivity and trace diffusion were seen in the AD patient population. These changes may be indicative of fiber loss and/or demyelination in the optic nerve.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.