Preliminary Evidence of Pronounced Thinning in the Cortex of Attention Deficit Hyperactivity Disorder Boys with a comorbid Reading Disability
Dhruman D Goradia 1 , Charles Frank 1 , Andrew Lorence 1 , Brianne Mohl 1 , Dalal Khatib 1 , Usha Rajan 1 , Arthur Robin 1 , David R Rosenberg 1 , and Jeffrey A Stanley 1
Department of Psychiatry and Behavioral
Neurosciences, Wayne State University School of
Medicine, Detroit, Michigan, United States
The prevalence of attention-deficit/hyperactivity
disorder (ADHD) with a comorbid reading disability (RD)
has been estimated to be as high as 45%. ADHD children
with RD tend to have greater severity in cognition;
however, morphological measures differentiating ADHD
with RD from ADHD without RD remains poorly understood.
The aim of this study is to investigate differences
between subgroups in cortical thickness of key
implicated areas in ADHD. As expected, ADHD with RD show
a greater extent of cortex thinning than ADHD without RD
in the prefrontal, parietal and cingulate areas, when
compared to healthy individuals.
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