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Abstract #1982

Fractional anisotropy in diffusion tensor imaging and diffusion kurtosis imaging at 3-T MR for detection of patients with depression and comorbid hypertension in depression

Ying Liu 1 , Huishu Yuan 1 , Xiangzhu Zeng 1 , Zheng Wang 1 , and Han Zhang 2

1 Radiology, Peking University Third Hospital, Beijing, Beijing, China, 2 The consultation liaison, Peking University Mental Health Institute, Beijing, Beijing, China

As important diagnostic tools for cerebral microstructure impairment, diffusion tensor imaging (DTI) and diffusion kurtosis imaging(DKI) have the ability to assess the white matter characteristics by investigating water diffusion with a Gaussian and a non Gaussian models. Fractional anisotropy is a very important parameter of DTI. Diffusion kurtosis imaging is an extension of diffusion tensor imaging. Fractional anisotropy of kurtosis (FAk) is similar to FA in DTI, and can be conveniently defined as FAk. The aim of this study is to evaluate the differences between depression and comorbid hypertension in depression using FA of DTI and FAk of DKI.

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