Abstract #1986
Abnormalities of cingulate cortex in antipsychotic-nave chronic schizophrenia
Xiaoyi Liu 1 , Yunyao Lai 1 , Xijin Wang 2 , Chuanxi Hao 1 , Lei Chen 1 , Zhenyu Zhou 1 , Xin Yu 2 , and Nan Hong 1
1
Peking University People's Hospital,
Beijing, China,
2
Institute
of Mental Health, Peking University, Beijing, China
In this study, we examined the sub divisional morphology
of cingulate cortex in antipsychotic-nave schizophrenia
by using a surface-based analysis. And we also
investigated the changes of morphology in cingulate
cortex and their associations with clinical variables
and cognitive performance. The results show that changes
of cingulate cortex play a critical role in
schizophrenia, and demonstrated that the left PCC volume
deficit may play a role in the working memory of the
disorder. And these are not attributable to
contamination by antipsychotic drugs.
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