Meeting Banner
Abstract #2018

Tissue outcome in areas surrounding the impact site in traumatic brain injury

Justin Alexander Long 1 , Lora Talley Watts 1 , Qiang Shen 1 , Shiliang Huang 1 , and Timothy Duong 1

1 Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

We previously reported heterogeneous perfusion disruption beyond the impact area following mild TBI. However, it is unclear how such hemodynamic disruption affects tissue outcome. This study evaluated the effects of perfusion deficit on ADC, T2 and FA by analyzing a series of ROIs away from to the impact area. MRI parameters did not changed when CBF dropped to 60% of normal, but changed only when CBF dropped below 20% of normal at 1-3hrs and 2 days post TBI. CBF recovered on day 14 and so did FA, ADC and T2 values, suggesting that this mild TBI model induces reversible injury.

This abstract and the presentation materials are available to members only; a login is required.

Join Here