Abstract #2026
Evaluation of Basilar Artery Atherosclerotic Plaque Distribution by 3D High Resolution MR Vessel Wall Imaging and Semi-Automatic Analysis Tool
Zhensen Chen 1 , Huijun Chen 1 , Aofei Liu 2 , Wei-Jian Jiang 2 , William Kerwin 3 , Chun Yuan 1,3 , and Xihai Zhao 1
1
Center for Biomedical Imaging Research &
Department of Biomedical Engineering, Tsinghua
University, Beijing, China,
2
New
Era Stroke Care and Research Institute, The Second
Artillery General Hospital PLA, Beijing, China,
3
Department
of Radiology, University of Washington, Seattle, WA,
United States
During stenting procedure of basilar artery (BA)
atherosclerosis, the plaque may be pushed and block the
ostia of the perforating arteries that usually originate
from the lateral or dorsal walls of BA, thus causing
severe ischemic events. Hence, assessment of BA plaque
distribution is important prior to stenting. This study
sought to develop a semi-automatic analysis tool to
comprehensively evaluate plaque characteristics,
particularly cross-sectional distribution, in 58
symptomatic patients. We found that >60% of BA plaques
mainly affected lateral or dorsal walls, suggesting the
necessity of evaluation of lesion distribution prior to
treatment using 3D MR vessel wall imaging.
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