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Abstract #2026

Evaluation of Basilar Artery Atherosclerotic Plaque Distribution by 3D High Resolution MR Vessel Wall Imaging and Semi-Automatic Analysis Tool

Zhensen Chen 1 , Huijun Chen 1 , Aofei Liu 2 , Wei-Jian Jiang 2 , William Kerwin 3 , Chun Yuan 1,3 , and Xihai Zhao 1

1 Center for Biomedical Imaging Research & Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2 New Era Stroke Care and Research Institute, The Second Artillery General Hospital PLA, Beijing, China, 3 Department of Radiology, University of Washington, Seattle, WA, United States

During stenting procedure of basilar artery (BA) atherosclerosis, the plaque may be pushed and block the ostia of the perforating arteries that usually originate from the lateral or dorsal walls of BA, thus causing severe ischemic events. Hence, assessment of BA plaque distribution is important prior to stenting. This study sought to develop a semi-automatic analysis tool to comprehensively evaluate plaque characteristics, particularly cross-sectional distribution, in 58 symptomatic patients. We found that >60% of BA plaques mainly affected lateral or dorsal walls, suggesting the necessity of evaluation of lesion distribution prior to treatment using 3D MR vessel wall imaging.

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