Abstract #2158

T1 relaxation of the liver; a new biochemical marker of liver function in patients with diffuse liver disease

Yukihisa Takayama ¹ , Akihiro Nishie ² , Yoshiki Asayama ² , Yasuhiro Ushijima ² , Nobuhiro Fujita ² , Koichiro Morita ² , Takashi Yoshiura ² , Tomoyuki Okuaki ³ , Makoto Obara ³ , and Hiroshi Honda ²

¹ Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ² Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ³ Philips Electronics Japan, Tokyo, Japan

We investigated the clinical utility of T1 lower case Greek rho

mapping for the assessment of liver function in patients with chronic liver diseases (CLD) by comparing T1 lower case Greek rho

mapping with patientsf blood serum parameters. T1 lower case Greek rho

value of the liver parenchyma showed significant correlations with serum albumin level, serum total and direct bilirubin levels, and ICG-R15 (the retention rate of indocyanine green 15 min after administration). Especially, T1 lower case Greek rho

values of the liver parenchyma were prolonged with increasing ICG-R15 which indicates a worsening of liver function. T1 lower case Greek rho

relaxation may server as a new biochemical marker of liver function.

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