Abstract #2226
Evaluating placental growth in normal murine pregnancy using tissue-similarity-mapping and dynamic contrast enhanced magnetic resonance imaging
Brijesh Kumar Yadav 1,2 , Uday Bhaskar Krishnamurthy 1,2 , Yimin Shen 1 , Jaladhar Neelavalli 1,2 , Gabor Szalai 3 , Bing Wang 3 , Tinnakorn Chaiworapongsa 3,4 , Edgar Hernandez-Andrade 3,4 , Nandor Gabor Than 3,4 , Ewart Mark Haacke 1,2 , and Roberto Romero 3
1
Department of Radiology, Wayne State
University, Detroit, Michigan, United States,
2
Department
of Biomedical Engineering, Wayne State University,
Detroit, Michigan, United States,
3
Perinatology
Research Branch, NICHD, NIH, DHHS., Wayne State
University, Detroit, Michigan, United States,
4
Department
of Obstetrics and Gynecology, Wayne State University,
Detroit, Michigan, United States
In this study, the longitudinal variations in the size
of high perfusion and low perfusion zones of the normal
murine placenta along different gestational ages are
quantified using dynamic contrast enhancement magnetic
resonance imaging(DCE-MRI) and an automatic segmentation
method based on Tissue Similarity Mapping (TSM.
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