Abstract #2258
Differentiation of Malignant from Benign Focal Splenic Lesions: Added Value of Diffusion-Weighted MR Imaging
Jiyoung Hwang 1 , Kyung Mi Jang 2 , Seong Hyun Kim 2 , and Mi Hee Lee 3
1
Department of Radiology, Soonchunhyang
University Seoul Hospital, Seoul, Seoul, Korea,
2
Department
of Radiology and Center for Imaging Science, Samsung
Medical Center, Sungkyunkwan University School of
Medicine, Seoul, Seoul, Korea,
3
Radiology,
Samsung Medical Center, Sungkyunkwan University, Seoul,
Seoul, Korea
Purpose: To evaluate the added value of
diffusion-weighted (DW) MR imaging for differentiating
between malignant and benign focal splenic lesions.
Methods: This study included 53 patients with 11
malignant and 42 benign splenic lesions and who
underwent gadoxetic acid-enhanced and DW MR imaging.
Qualitative and quantitative analyses were conducted for
splenic lesions. Results: All malignant lesions showed a
hypovascular progressive enhancement pattern, while
hypervascular enhancement patterns were only
demonstrated in benign lesions (20, 47.6%) (P<0.05). The
mean ADC of malignant lesions was lower than that of
benign lesions (P< .001). The addition of DW images to
conventional MR images showed a significant improvement
for predicting malignant splenic lesions (P < 0.001)
Conclusion: The addition of DW imaging to conventional
MR imaging improves differentiation of malignant from
benign splenic lesions.
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