Meeting Banner
Abstract #2298

High-resolution MRI of hyperpolarized propane at 4.7 T and 0.0475 T

Kirill V Kovtunov 1 , Milton L Truong 2 , Aaron M Coffey 2 , Danila A Barskiy 1 , Igor V Koptyug 1 , Kevin W Waddell 2 , and Eduard Y. Chekmenev 2

1 International Tomography Center, Novosibirsk, Novosibirsk, Russian Federation, 2 Radiology, Vanderbilt University, Nashville, TN, United States

Fast (TR<4 ms) hyperpolarized proton MRI is presented for non-toxic propane gas prepared by heterogeneous parahydrogen induced polarization using Rh/TiO 2 solid state catalyst. 3D imaging with 0.5x0.5x0.5 mm 3 is demonstrated using ~1% 1H hyperpolarized propane at 4.7 T preclinical MRI system with relatively large field of view 48x48x32 mm 3 . Feasibility of sub-second sub-millimeter (0.9x0.9 mm 2 ) 2D imaging of hyperpolarized propane (polarization P=0.3%) is also demonstrated at 0.0475 T preclinical MRI using frequency optimized RF coils. Hyperpolarized propane MRI can potentially be used for economical high-throughput low-field functional MRI of human lungs.

This abstract and the presentation materials are available to members only; a login is required.

Join Here