Abstract #2299
Rapid Pulmonary Proton ZTE Imaging in the Mouse
Mingming Wu 1,2 , Markus Weiger 1 , Moritz Christoph Wurnig 3 , Wolfgang Jungraithmayr 4 , Andreas Boss 3 , and Klaas Paul Pruessmann 1
1
Institute for Biomedical Engineering,
University and ETH Zurich, Zurich, Switzerland,
2
Institute
of Biomedical Engineering, Karlsruhe Institute of
Technology, Karlsruhe, Germany,
3
Department
of Diagnostic and Interventional Radiology, University
Hospital Zurich, Zurich, Switzerland,
4
Division
of Thoracic Surgery, University Hospital Zurich, Zurich,
Switzerland
Pulmonary proton MRI is conducted in mice using zero
echo time (ZTE) imaging. Scan times of only 81 s for a
3D image with matrix size of 160 and isotropic
resolution of 0.31 mm are achieved, yielding an SNR of
8. Further improvement of image quality is accomplished
using respiratory-triggering and/or averaging at the
expense of higher scan times. Additionally, ZTE imaging
is demonstrated to enable T1 mapping in short T2 tissue
such as in the lung where a T1 value of 660 ms is found.
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