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Abstract #2299

Rapid Pulmonary Proton ZTE Imaging in the Mouse

Mingming Wu 1,2 , Markus Weiger 1 , Moritz Christoph Wurnig 3 , Wolfgang Jungraithmayr 4 , Andreas Boss 3 , and Klaas Paul Pruessmann 1

1 Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2 Institute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany, 3 Department of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland, 4 Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland

Pulmonary proton MRI is conducted in mice using zero echo time (ZTE) imaging. Scan times of only 81 s for a 3D image with matrix size of 160 and isotropic resolution of 0.31 mm are achieved, yielding an SNR of 8. Further improvement of image quality is accomplished using respiratory-triggering and/or averaging at the expense of higher scan times. Additionally, ZTE imaging is demonstrated to enable T1 mapping in short T2 tissue such as in the lung where a T1 value of 660 ms is found.

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