Abstract #2303
Highly Reseolved Imaging of Hyperpolarized Helium-3 Ventilation Dynamics using fast 3-d UTE and k-t PCA
Andrew D Hahn 1 , Kevin M Johnson 2 , Grzegorz Bauman 3 , Robert Cadman 2 , Talissa A Altes 4 , and Sean B Fain 2
1
Department of Medical Physics, University of
Wisconsin, Madison, Madison, Wisconsin, United States,
2
Department
of Medical Physics, University of Wisconsin, Madison,
Wisconsin, United States,
3
Department
of Radiology, University of Wisconsin, Madison,
Wisconsin, United States,
4
Department
of Radiology and Medical Imaging, University of Virginia
School of Medicine, Virginia, United States
Hyperpolarized helium-3 gas inhalation and exhalation
dynamics were recovered with high spatiotemporal
resolution in a swine model utilizing a fast 3D radial
UTE MRI sequence and reconstructed using k-t PCA. This
technique could provide a more robust framework for
investigating functional ventilation in young children
who may not be able to maintain breath hold or lay still
for an extended period.
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