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Abstract #2344

Spatial and Temporal Characteristics of Soft Tissue Heating in MR-HIFU Treatment of Bone Metastasis

Taylor D Webb 1 , Rachelle Bitton 2 , Pejman Ghanouni 2 , and Kim Butts Pauly 2

1 Electrical Engineering, Stanford University, Stanford, CA, United States, 2 Radiology, Stanford University, Stanford, CA, United States

We investigated the impact of heat radiation from bone during the high intensity focused ultrasound treatment of a patient with metastatic tumor in the bone. Extra images were acquired post sonication to allow for better understanding of the temporal characteristics of the temperature in the soft tissue. We show that temperature rise in the soft tissue adjacent to the bone is delayed with respect to the sonication. Additionally, our spatial analysis of the temperature over time reveals that radiation from bone causes slower temperature decay, leading to higher dose accumulations and necessitating longer cooling times between sonications.

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