Abstract #2344
Spatial and Temporal Characteristics of Soft Tissue Heating in MR-HIFU Treatment of Bone Metastasis
Taylor D Webb 1 , Rachelle Bitton 2 , Pejman Ghanouni 2 , and Kim Butts Pauly 2
1
Electrical Engineering, Stanford University,
Stanford, CA, United States,
2
Radiology,
Stanford University, Stanford, CA, United States
We investigated the impact of heat radiation from bone
during the high intensity focused ultrasound treatment
of a patient with metastatic tumor in the bone. Extra
images were acquired post sonication to allow for better
understanding of the temporal characteristics of the
temperature in the soft tissue. We show that temperature
rise in the soft tissue adjacent to the bone is delayed
with respect to the sonication. Additionally, our
spatial analysis of the temperature over time reveals
that radiation from bone causes slower temperature
decay, leading to higher dose accumulations and
necessitating longer cooling times between sonications.
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