Correction for heart rate bias of post-contrast myocardial T1 values derived using MOLLI sequence
Neville D Gai 1 , Fabio Raman 1 , and David Bluemke 1,2
Radiology & Imaging Sciences, NIH, Bethesda,
Maryland, United States,
Bethesda, Maryland, United States
Post-contrast myocardial T1 values and associated
measures such as extracellular space (ECV) can show
variation due to the acquisition scheme. In particular
variation due to heart rate results in biased values for
T1. We show that this bias can exhibit a systematic
relationship with heart rate. An
is proposed which would allow for comparison of T1
values between subjects with varying heart rates.
Results of a phantom study are presented to illustrate
our correction method.
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