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Abstract #2421

Correction for heart rate bias of post-contrast myocardial T1 values derived using MOLLI sequence

Neville D Gai 1 , Fabio Raman 1 , and David Bluemke 1,2

1 Radiology & Imaging Sciences, NIH, Bethesda, Maryland, United States, 2 NIBIB, Bethesda, Maryland, United States

Post-contrast myocardial T1 values and associated measures such as extracellular space (ECV) can show variation due to the acquisition scheme. In particular variation due to heart rate results in biased values for T1. We show that this bias can exhibit a systematic relationship with heart rate. An ex post facto solution is proposed which would allow for comparison of T1 values between subjects with varying heart rates. Results of a phantom study are presented to illustrate our correction method.

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